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What is this project about?

The purpose of the SKOAP study is to compare different treatments for people living with knee osteoarthritis. The goal is to reduce pain and improve function using conservative treatments and, if needed, non-surgical procedural interventions that have been shown to reduce pain.

This study is approved by the Johns Hopkins Institutional Review Board (IRB00238678). The principal investigators for this project are Steven Cohen, MD, Claudia Campbell, PhD, and Renan Castillo, PhD.

Chiropractic Treatment

Am I eligible to participate?

We are looking for volunteers who are between ages 18-90, have been diagnosed with knee osteoarthritis, and have had knee pain for most days for at least 3 months. Please take this screener to find out if you might be eligible. 

What will I be asked to do for this study?

Your participation in this study will involve: (1) questionnaires, (2) random assignment to treatment(s), and (3) online follow-ups. 

  • There are up to 7 study visits that can be completed in person at the Johns Hopkins Pain Clinic or via telemedicine visit.

How will I benefit from this study? Will I be compensated for my time and how much does it cost to participate?

Participating may reduce your pain, improve knee function, and quality of life without surgery. Additionally, this is an opportunity to try different state of the art treatments for knee pain and contribute to chronic pain research, which can help others with your condition.


If eligible, you may earn $510+ for completing all study-related visits, and we will cover parking expenses.

This study is meant to follow a patient as they receive standard of care visits/procedures. The study does not pay for medical procedures or visit copays. Participants are responsible for paying insurance co-pays or out-of-pocket for medical procedures. 

How can I find out more information?

For more information, please visit SKOAP's website. You may contact our team directly by calling Heavon Allen at 410-550-1217 or Sydney Jensen at 410-550-4225. You can also reach us via email at

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